Real talcum powder has been removed from the US market because of contamination with asbestos. Most of what you can buy now is actually corn starch scented to smell like the old baby powder.
Rule #1 when dealing with a pest. Know their habitat requirements and make the habitat as inhospitable as possible.
With
ants, I find that the ant mound torches are a good option if you are not in a fire prone area or time of year. It's best to use when its a bit damp and not windy. It injects propane into the mound and then
lights it to consume all the oxygen and suffocate the little biters.
The borax tainted sugar
water works too but keep it away from pets.
Alternatively, there is a guy on youtube that will fill their mound with molten metal to create the most amazing sculptures.