Yes, you can! The inulin can be converted to digestible sugars through a few pathways such as boiling, soaking in something acid like lemon juice or vinegar (pickling), or freezing (you can toss them in the freezer but I just let our frosts take care of that). After that the calories are closer to those produced by potatoes.
How do I know? I grew a lot and ate a lot this winter. Usually we have a cold January and very cold February so I loaded up heavily during December. By that I mean my main food in most of my meals were usually sunchokes. I fixed them up in many, many ways (soup, bread, pizza crust and toppings, sunchoke taco with the sunchoke shells, crackers, toppings, fried like hash browns, fries, hash brown casserole, fruit salad after they were cooked a bit, ate them raw but I ate a huge bowl early on in the year and got cleaned out but your body adapts to the inulin over time but I'll start small next year and work up lol). What happened is that I gained ten pounds going from a very active 140 to 150 male!
Our January and February was mild this year and I had greens (brassicas, dock, etc) all year but I had stored a lot of sorghum, amaranth, sweet potatoes and potatoes and decided to stop digging sunchokes as much during those months. I plan on canning some but not enough for the year.