St. Johnswort does speed up one of the liver detoxification pathways, increasing the effective dose of pharmaceuticals (because the drug is cleared from your body faster). I believe most trials on this, including those listed in Treasure's work, used standardized extracts of St Johns. The tea will not have as strong an effect in this regard, but it's probably still a good idea to ask your doctor if you're on any life-dependent drugs, e.g. blood thinners or blood pressure regulators, before beginning a regimen with St Johns (also note that it may affect the dose of oral contraceptives!)
I would want to know more about the depression, diet, lifestyle, etc before recommending other herbs that could help. One thing you could try, however, is supplementing with the mood chemical precursors. I've found that supplementing with 5-HTP (precursor to serotonin and melatonin, metabolized from tryptophan) and Tyrosine (precursor to dopamine, adrenaline, noradrenaline, thyroid hormones, etc) helps withdrawal symptoms for those experiencing haziness and depressed mood after long-term cannabis use. It's worth a shot. Tulsi/Holy Basil is also a great herb for bringing clarity to the mind and opening the lungs (increased respiration = more connection with heart-centered consciousness). Try a tea of Tulsi and Rose petals to help bring calm to mind and heart.
Meditation and removing all possible stressors will also help.
I've attached Treasure's work on St Johns if anyone is interested in reading through the full scientific explanation.
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