I've had them together before. They were slightly harassing to the rooster at first but down the road, when he was challenged by a new rooster, they actually defended him...he didn't have to lift a finger, wing or whatever. The hens and the Guineas always got along. Because of their flight, they were able to come and go as they please, even if the chickens were kept in the pen for the day. They are noisy, especially as darkness falls. During the day, they alert to anything out of the ordinary. In late evening, they alert to anything that moves. Their demise came at the jaws of Jack, my chicken protecting dog, who would never harm a feather on a chicken...he just refused to tolerate their insolence. Consequently, they've never been replaced.