Hi...I’m in SW Va just west of Martinsville in the Piedmont. One of my orchards faces south. I grow a lot of apples, but also peaches, plums, pears and I planted quince because they looked cool. It’s is on a bit of a slope, very minor but still sloped enough for water to run. My trees have done extremely well, with no supplemental water except for 1st year trees. With these I use my Polaris with a water tank on the back and water when necessary. After year one, they are on their own. I’m diligent about staying on top of diseases and insects, and I do spray, only during periods where the risk is greatest (blossom season...for fire blight, when cedar gals are out for cedar rust and when the Japanese beetles show up because they will stress the trees terribly). My spray regime goes from about April into early July. I knock fruit off young trees, if they fruit ... to ensure the energy goes into growth.
I also grow almonds (have not gotten any yet...year 5 and 2 2 trees because I really wasn’t sure they could survive), chestnuts (year 5 and I got some a year ago and a lot this past fall - Dunstan Chestnuts), and I planted pecans 2 years ago. I’ve planted pecans before and they are REALLY slow growing. These require a lot of water regularly and the best tree I ever had did well just downhill from my septic field...so... This one is about 40 feet high and 20mfeet wide, and my buddy’s trees which we bought together and planted at the same time are maybe 15 feet tall and kind of scrawny in comparison. Oh, if you plan to do this plan to dig the deepest hole you have ever dug for a tree (huge tap root).
As for planting among other trees..never did that.
Lastly, I pay attention to the soil and have it tested by Va Tech thru the ag-extension. You may be shocked by how low your PH is...and this isn’t good for most plants...weeds seem ok w it!
I hope this helps you.