Mike Lansing

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since Sep 23, 2017
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Recent posts by Mike Lansing

In 2006, badger2 was fortunate to meet Dr. Willy Burgdorfer, discoverer of the Lyme disease agent, and Dr. Philip who wrote a book on Rocky Mountain Spotted Fever. Dr, Philip spoke at length on Colorado tick fever, which is a calicivirus. Here via the Maackia trajectory, we link Colorado tick fever to Louisiana where the Maackia plantation was established:

Maackia Lectins / Sambucus nigra / Influenza
https://www.ncbi.nlm.nih.gov/pubmed/28712489

Maackia / Tulane Calicivirus
https://www.ncbi.nlm.nih.gov/pubmed/26146020
7 years ago
'The Great Pandemic of 1889-1890. Eastern Siberia was threatened by influenza advancing from the steppes of West Siberia. Moving along the route later to be followed by the Trans-Siberian Railroad, influenza spread beyond Lake Baikal to Chita by Christmas of 1889 and to Sretinsk (Sretensk) on the Upper Amur River in January. Here the eastward course of the disease stopped, perhaps because the Amur, used by steamers for the next segment of the route to the Pacific, was frozen. Influenza did move north to Yakutsk.'
(Patterson KD, Pandemic Influenza, 1700-1900. A Study in Historical Epidemiology, Totawa, NJ: Rowman & Littlefield [1986] pp. 49-65)

Maackia has been planted in Louisiana.

Maackia amurensis
https://en.wikipedia.org/wiki/Maackia_amurensis

Maackia links precisely to the chemistry shown here, which strongly suggest that the butterfly Papilio maackii is ingesting anti-influenza compounds. What are the food plants of P. maackii?

Pterocarpans and Flavanones from Sophora flavescens Displaying Potent Neuraminidase Inhibition
http://www.ncbi.nlm.nih.gov/pubmed/18938076
7 years ago
In the video, Stamets invokes p-coumaric acid. Therefore, we will wrest away from him any attempt to reify p-coumaric acid as unique to the Northwest Coast. Euptoieta claudia feeds on Viola species. Viola contains p-coumaric acid. We have mentioned on the Smerinthus thread the highly methylated exudates from Populus buds.

Fungal Metabolites Against Skin Cancer / Trichoderma
http://www.ncbi.nlm.nih.gov/pubmed/22991673
'....methyl ester was the most potent....'

Basal cell carcinoma (BCC) uses collagenase to advance through human tissue. This report from Japan links the chemistry of the Gulf Fritillary, Euptoieta claudia, to collagenase inhibition, and notice (both cis and trans [italics]) configurations of the molecule:

Jan 2013 Japan / Viola yedoensis / Collagenase Inhibition
http://www.ncbi.nlm.nih.gov/pubmed/22529049

An interesting fungal link to p-coumaric acid is here:

2017 / Conocephalum / p-Coumaric Acid / Sabinene
http://www.ncbi.nlm.nih.gov/pubmed/11193385

Finally, p-coumaric acid links to a Japanese Papilio for sabinene, and (this [it.]), as we will show, is the link to influenza viruses:

Odawa, Japan / Papilio maackii Secretions
http://www.ncbi.nlm.nih.gov/pubmed/24420834
7 years ago