Where I live is the best place to be, for me, because I was born here and my family has been here a few generations.
I feel like I belong to this bit of land in my heart - - (as a young man I had dreams of moving to Costa Rica and being a Fruitarian, but I couldn't bring myself to abandon my home place.)...
I feel like I was made for this valley, although my Vata body type is truly more suited to the Tropics.
The cold and very rainy winters and dry summers of this area may dismay others, but I've come to appreciate each season.
May-June & September-October are spectacular and sublime here, though.
In addition to being tied here by family bonds, the land in which I dwell seems to support abundant plant growth too.
So in conclusion, my reason for this being the best place for me is less to do with ideal permaculture conditions and more to do with family and spiritual feelings, and convenience. However, I expect that a lot of people (perhaps a majority?) don't feel a special love or affinity or tether to the place they were born.
Having travelled around the states though, and British Columbia too, I found many lovely and beautiful places, but I never found a place I liked better than Home.