It's my personal theory that many modern diseases and disorders will prove to be metabolic and caused by deficiencies and stress from poor diet and other conditions of modern (or civilized) life.
Much of what we have been told (theories based on incomplete research) about cholesterol and the many kinds of heart disease are proving to be false. The body manufactures cholesterol, much as it manufactures white blood cells, to fight something amiss in our bodies.
I read somewhere that NIH is re-evaluating/studying the daily amount of Vitamin D needed in most of the US, saying it could be 5,000 IU (or more) daily rather than the current RDA of 400 IU.