I have always liked the variety of vegetables as well as the plethora of choices in a given variety. The one things I have had trouble with is the percentage of germination. Sometimes, I get 90%+ germination of a given seed pack, but others do not hardly get 50%. I will admit that I do not have good statistics on which ones I had trouble with, but the pepper varieties seem to be the ones I had trouble with. Additionally, the lettuce and pepper variety packs tend to be slanted toward one of the varieties in the pack.
If no one else has had this problem, then feel free to contradict me. I am just a backyard gardener, for my own consumption, so I also buy small packets of seeds.