The whole area is at higher risk for tornadoes, especially the I-44 corridor from OKC to St. Louis. That said, Rolla, MO is nice town. University of Missouri, Rolla makes it much more interesting than anyplace else along I-44 (IMHO).
The downside of land in southern Missouri is that there is not much soil on top of all that limestone. If you can find a low-lying piece that has a (seasonal) creek running through it, that would be your best bet. Also take note of the size of the white oaks on the property. If you have a lot of white oak, a
local sawmill will pay you well for that, and then you have some money you can put back into planting your diverse food forest. If you are really fortunate, there may be marketable black walnut on it, and those
trees can bring in some serious money. If it has a lot of scrubby
black locust and osage orange (hedge
apple), that's not going to get you any money, but you will have plenty of starting material for
hugelkultur and/or
biochar.