GMO and hybrid and quite different. Hybrids are crosses between two pure-bred varieties - the result is often an exceptionally vigorous variety, the downside is that any propagation by seed won't produce plants similar to the parent. That shouldn't be a problem with grapes which you would typically propagate by cuttings.
Currently there are no approved GMO grapes out there, so no need to worry.
Isaac Hill wrote:Eric Toensmeier had this wonderful idea: Take walks in the summer and look out for wild grapes that are large/sweet. Mark them with something, like a piece of colored tape or whatnot, and come back for a cutting when they're dormant. That way you have your own heirloom grapes that are perfectly bred for your climate!
I live near Morraine State Park and this past fall harvested an excess branch or two from some of the grapes growing there. these were grapes that were planted on the old farms there before the area was made a state park. some vines have been growing on their own for at least 60 years and other younger vines propulgated by the birds and animals. all producing good fruit without pruning, spraying or fertilizer. the bike trail on the north shore is loaded with them. the park actually mows some of them back to keep them from overgrowing the trail, so a few prunings is not a problem. one branch can produce a number of cuttings to start.
I have removed several well established wild grapevines from my property in an effort to cut down on future beetle populations.