Grafting Solanum like tomatoes, peppers and potatoes.

I once scoffed at the idea of small scale growers grafting annuals, but the imperatives of greenhouse growing made me rethink my kneejerk reaction.
Every time we improve bit of land it becomes more precious, and we should chose our plant tenants accordingly.
This pomato video reports a good yield on both the tomato and potatoes ends, but the tomatoes end  did better than they do on their own roots:

Combine that with the idea that potatoes can be started outside under cover incredibly early, and you are looking at a something worth doing.

The next logical step is grafting tomatoes to a hardy perennial  Solanum, but I cant find anything on that as of yet.
The next best thing would be grafting onto a perennial that could over winter indoors.
Tamarillo is the obvious choice, but I've found nothing on this either.
Can annual ever  be grafted onto perennials?
All I've found  to answer this question is this: Experiment Station Record, Volume 5

So, what I take from all  this is I should try this with potatoes, ideally  early  earlies.
I might also try to get some of the special "rootstock" tomatoes, just to see what they produce on their own.

I tried grafting a mix of indeterminate heirlooms to Maxifort rootstocks about 4 or 5 years ago. I had problems with mold that developed within a day or so under the dome they were covered with. I had taken the dome off for a few hours but that evidently wasn't enough. I usually grow my seedlings in a south window without the dome and with a heat outlet below it and I think the airflow would maybe help with growing the grafts.

I also had trouble with the rootstocks growing much faster than the scions. I had planted the scions before the rootstocks and had planted some with varying days. If I grafted again I would try planting rootstocks over a number of weeks later than the tomato varieties to hopefully find size matches

The New Yorker ran an artilcle on May 15, 1965. The article. The general gist is that a family got really really sick and delusional after eating tomatoes from a plant grafted onto a jimsonweed plant. So just don't use a toxic plant to do it with hmmm? We need all of our Permie people!

You make a good point!!
There are rootstock,  like the giant potato tree, that are poisonous but don't impart that to the fruit.
Safely discovering new plants like that is probably beyond most of us.