DCA site, cancer cure studies

This was a real breakthru a few years ago, but not many follow up studies because it is cheap, and has side effects.

You can usually lower doses of all drugs that need to go inter-cellular by taking them while having magnolia bark tea.
The magnolia slows the pumping out action in cells, i dont know if it is the calcium/magnesium pump just described in the medical press.

Do your homework....
And don't take my advice as medical theory !

http://www.thedcasite.com/

oops, here is some background on the magnolia bark.

http://www.mdidea.com/products/herbextract/magnolia/research.html

http://www.whsc.emory.edu/press_releases2.cfm?announcement_id_seq=14964

http://www.henriettesherbal.com/eclectic/dmna/magnolia.html

and reports from the field.
they don't say these are controlled studies, just in vivo use

http://www.medicorcancer.com/dca-reports.html

another activator to be careful with. this is probobly extra dangerous with DCA, so no Grapefruit for you !

http://www.sciencedaily.com/releases/2012/11/121126143001.htm

Archea blood for you !

from the archea thread

Dont know if related to the DCA mechanism, since we don't know how THAT is supposed to work.
But since the article talks about changing out the lipids "heads", maybe there is a pathway there.


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465877/

@Morgan

What is that link leading to? Is it about cancer?

Is a cancer vaccine., for ones that you can attack with T cells.

the lipid structuring is big this year, they have learned how to trade out the "heads" fairly easily. the archaeol is the carrier, and wakes up the T cells to attack.
there are only 3 major archea in the body that are tolerated. (well, 4 now).


Conclusion
Finally, long-term immunity was obtained in an archaeol-based lipid archaeosome lacking caldarchaeols. We conclude that for a cancer or intracellular pathogen vaccine where a CD8+ T cell response is needed, a favorable archaeosome composition is gentiotriosylarchaeol, mannotriosylarchaeol, AS, and PGP in mol% ratio 22.5/22.5/30/25.

DCA you tub link for many news shows with the doc.
Stage 1 supposedly cleared.
Has been used on kids for some very rare diseases.

This is great, using intersecting ultrasound beams to heat and kill tumors, without surgery.

http://medicalxpress.com/news/2013-06-therapy-bone-tumors-eases-patients.html


and this is an interesting combination therapy, because it is just activating markers, so T cells can go after them.
This might be one of the least dangerous chemo directions, but havn't checked for side effects yet.

http://medicalxpress.com/news/2013-06-combination-drugs-tumor-responses-advanced.html

This is why standard cancer therapy is so hard, and is easier to get the immune system to go after the bad cells

MAPK pathways

http://upload.wikimedia.org/wikipedia/commons/b/b4/MAPKpathway.jpg

latest papers on DCA at NAS

http://www.pnas.org/search?fulltext=+Dichloroacetate&submit=yes&x=0&y=0

and one of the papers looking at the disabling the Warburg effect, to allow deionisation of the lipid barriers that protect the cells from apotasis

http://www.pnas.org/content/106/52/22199.full.pdf+html?sid=19913791-141d-469a-9d9d-9e93dc917265

and a possible mechanism of effectivness. This may be the original paper. check sites list of papers to make sure.

http://www.pnas.org/content/79/17/5292.full.pdf


not much new in Nature
http://www.nature.com/search/executeSearch?sp-q-1=&sp-q=dichloroacetate&sp-p=all&sp-c=25&sp-m=0&sp-s=&sp-a=sp1001702d&sp-sfvl-field=subject|ujournal&sp-x-1=ujournal&sp-p-1=phrase&submit=go


dont know if this satisfies the studies study tho....

Why most research findings are false.

http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0020124

Interesting that these snails use a copper based blood serum, instead of iron, and seems to work on many cancers....

http://www.united-academics.org/magazine/health-medicine/cancer-vaccines-from-mollusk/

more on the immunotherapy angle of using your own t-cells to attack.
(from above)
http://medicalxpress.com/news/2013-06-combination-drugs-tumor-responses-advanced.html

Typically discussed as cancer vaccines, and there are a bunch in trials now that use the PD1

http://www.newscientist.com/article/dn23646-antibody-wakes-up-tcells-to-make-cancer-vanish.html?full=true&print=true

one of the leading news sites on research news ?
http://www.fiercebiotech.com/news

and their top 10

http://www.fiercebiotech.com/special-reports/top-10-experimental-cancer-drugs-2013?page=full

These ligand/lipid angles sure look like they could be home brewed.

The one above on PNAS that discusses linking the platinum to DCA, might work just linking the DCA to VitC, and enclosing it in lipisome by the same ultrasonic cleaner/lecithin trick used for lipasomal Vit C.

Will be looking into it, I want to see if there are interactions between Citric Acid and Vit c also.

Osteoporosis drug, Bazedoxifene, like tamoxifen, stops breast cancer by estrogen binding, and killing estrogen receptors.

http://m.medicalxpress.com/news/2013-06-osteoporosis-drug-growth-breast-cancer.html

Sodium dichloroacetate can be really helpful for someone with Glioblastoma as additional chemotherapy treatment with TMZ.

I see you're talking about estrogen cancer inhibitors. What can I say about this subject regarding DCA.
It can aid Tamoxifen treatment in breast cancer. It can help against non-small cell lung cancer, prostate, ovary, neuroblastoma and other cancers. I have been following this substance for a couple of years now since my close friends decided to use this stuff.

A lot of people have been noting that there are no news on DCA. That's relatively true. The DCASite and DcaWatch are unactive for some time. I advise you to give it a try in http://www.DcaGuide.org on the internet or maybe on facebook. Search youtube, search databases.

DCA can be used a monotherapy or in a combination with other treatments. Look up www.DcaGuide.org .They are known to post such possibilities as well as other great information on usage, dosing and other things.

There have been frauds on Fake DCA on the internet - If you plan to buy it, I advise you to do so on Amazon. This has a strict product policy and you can buy pure and well prized products (etc. https://www.amazon.com/dp/B06Y45T656/ref=cm_sw_r_cp_ep_dp_bJq1zbDMP2AAR )

So yeah, DCA can help some cancers. The problem is that it is so bloody cheap and unpatentable - no one wants to invest money for clinical research with this stuff. It costs about 1 billion $ and takes about 5 - 10 years to provide the world with a approved legit drug. DCA wont be able to bring so much cash so it will probably never undergo the procedures it needs to become a valid drug. We must remember that it was already used as a drug for the reasons mentioned above, just not for cancer. ( http://www.dcaguide.org/dca-history-and-usage )