Hi Brenda...
Yes... disease is an issue... In polycultures there are a lot of unknown factors going on and some are helping reduce disease incedence...
Long-term there are two things that we should once again turn to nature for the answers...
One is succession... the Prunus genus is a mid-succession plant. It gives way to shade tolerants and in the case of MI would give way to the northern hardwoods... Sugar maple, beech, yellow birch, eastern hemlock... Somehow you've got to change the conditions so that the prunus diseases are not an issue...
The biggest thing that we need to do is breed new varieties... Using Luther Burbank style mass-selection (read about it in Restoration Agriculture:
http://www.forestag.com/book.html )
Buying the same old susceptible cultivars just ain't gonna cut it... Stop trying to keep things alive that want to die and stop fighting against the things that want to live... Plant a zillion seedlings and let the losers die. The only ones that can survive on your site will have some sort of resistance trick...
SO... I would address the issue either by going past the prunus phase of succession or start a massive seedling breeding program... HEre's a great way to get a seedling nursery started in a small space...
http://littlehouseontheurbanprairie.wordpress.com/2010/11/06/chestnuts-and-hazels-for-the-future/