A variety is nice, my first set on the farm are in a vaguely sun-scoop shape around a
pond.
In a smaller, shadier space at my parents place, I built one east-west, and one north-south. In that shady site, the north-south didn't work great; any added shading was Bad News, and the south end was too small to be useful, and too close to the shaded edge of the garden. After a year I built some log walls around it and converted to a raised bed, which worked very well.
The east-west one worked better, but growing on the north was a lost cause. I used
pallets to enclose just the north side, and gave the whole thing a south-facing slope, which worked out nicely.