I say go with two layers overlapped to seal up the seams. I don't think you need to worry much about compression with Foamular. It's really made for applications like that and can hold up fine under pressure. I definitely wouldn't put it under a tire wall though, unless it's part of a specially engineered concrete footer or something.
As for insulating the slab, that's a hotly debated topic. The folks in Taos recommended against it for my build, rightly pointing out that it would cut off a huge part of the thermal battery. I live in a very wet location though, so I'm considering using this stuff under the sub-floor:
http://www.thebarrier.com
How high is the water table at your build site? As long as you're more than 5 feet above year round, it may be more effective to spend that money on extra drainage to keep the thermal wrap dry (french drain around the whole perimeter). Definitely stick with at least R-20 XPS for the thermal wrap.
-ian