If you're looking at land between Appalachia and the Rockies, you may want to consider weather as well as other things. As a matter of fact, that's on the top 5 of my list.
Why?
TORNADOES - sat through many in the school halls as a kid and had one go over my 3 acre homestead and take out a brick storage building on a cattle ranch less than 3 miles down the road from me.
There's also the other weather constraints - winter lows and polar vortex dipping down out of the artic (fall is harvest and winter prep time, and will you go out in minus temps to take care of things); annual rainfall and water catchment laws (plants do better with rain water than well water - Ph balance); summer heat and length of time between rain during your growing season (sucks to lose plants to heat and drought after all of the initial planting and optimism). Have you looked at these and started contengency plans?
Granted a cabin in the middle of nowhere sounds great, but what about wildfires? And where's your market located for your products/services; how far away is it; transportation and time costs; potable water with well testing if required in that area; other logistical considerations ? My husband wanted the cabin in BFE until I pointed out that the mountain man/lone wolf from the movies does not work for farming, and besides how many of those mountain men/lone wolves died without anyone even knowing they had existed out there? (I worked in movies & TV for several years - 200+ people to make a show about 3 people. Now figure how many people will it take for your farm to break even?)
Unless you're independently wealthy, farming is a community activity and a real business that can go broke way too fast and easy. If you're planning a permaculture training and retreat - check local agritourism & hospitality laws; also liability insurance.
Also look at the way local and state government treat agricultural businesses and farmers in the area you're looking to move to. Most municipalities want businesses, homes and industries - not farms, for tax revenue. Farms are lower income for towns and counties and so they can have more restrictions in some areas than others.
Just realize that there is more to finding the right property than
cost per acre. Up front, a property may seem a deal, but it's the residual and back end costs that you need to keep in mind.
Good luck on your dreams and goals
R