Graham Chiu wrote:
Trace Oswald wrote:The other side of this is that there are currently existing drugs showing real promise against the virus, including the treatment of people that are already critically ill. Kaletra and Hydroxychloroquine are two of them.
Until someone publishes a controlled series of their outcomes then this is just hearsay.
There's a group in Australia saying this combination effectively treated their patients but until they publish somewhere ...
Roberto pokachinni wrote:[..... a quick quiz to let you test yourself ....
The duration of incubation is an average of 5 days, with extremes of 2 to 12 days. The onset of symptoms appears gradually over several days, unlike the flu which starts suddenly.
The first symptoms are not very specific: headache, muscle pain, fatigue/tiredness. Fever and respiratory signs occur secondarily, often two or three days after the first symptoms.
In the first descriptive studies from China, an average of one week elapsed between the onset of the first symptoms and admission to the hospital in the disease phase. At this stage, the symptoms combine fever, cough, chest pains and respiratory discomfort. The performance of a chest scanner almost always shows pneumonia affecting both lungs.
The severity of clinical signs requires that approximately 20% of patients remain in hospital and 5% require admission to intensive care. The most serious forms are observed mainly in people who are vulnerable because of their age (over 70) or associated diseases.
Specific observational studies (such as the one carried out on passengers on the Diamond Princess cruise ship) as well as modeling work have shown that the infection can be asymptomatic or paucisymptomatic (causing little or no clinical manifestations) in 30 to 60% of infected subjects.
Graham Chiu wrote:About 1:10 infections are from people who are infected by asymptomatic patients. Because they think they're well, they are acting normally and so potentially spreading this bug more.
The highest viral shedding is in the pre-symptomatic phase.
Once you're symptomatic your immune system is helping shut down viral numbers and so you shed less virus.
It doesn't appear to be passed by the fecal route.
Cough induction for sputum collection is being advised against as it aerolizes the virus into the environment. This was from a CDC webinar.
Jen Fan wrote:
So the CDC information web page states that pre-symptomatic people are 'unlikely' to spread the virus.
Roberto pokachinni wrote:
While wearing a mask is potentially helpful to keep the droplets out of your personal respiratory tract, they are much more effectively used to stop infectious people from coughing the droplets outwards. One can not where a mask all the time, and they become dirty and contaminated and need changing. In an ideal world, everybody should be given masks and be able to use them when out in public, but the current situation is far from ideal... The biggest problem with masks at this time, is that they are in very limited supply (this is especially an acute problem due to hoarding). Doctors, nurses, care-aids, and patients with infectious coughs are the ones who these limited resources should be concentrated on.
If you bought a box of masks, I'd suggest getting them to a hospital, a health clinic, or a doctor's office where they can be put to the best possible use.
Huxley Harter wrote:What do you think is the future of the new virus? Is the majority of the population overreacting? Underreacting?
How are you dealing with the threat (if it is)?
Please be nice and remember that opinion is opinion, not objective truth.
Nicole Alderman wrote:Wearing a mask is great if you can make it yourself. Please, please, PLEASE don't buy them from the store. I say this as someone who's husband works at the hospital. They don't have enough masks. If a patient is not confirmed as Covid-19 positive, he is not allowed to wear a mask. And with the positive patients, he is only allowed a paper mask, which he has to reuse on 5 patients before getting another one...and this is while he's bent over them while they're coughing and sick.
Masks are rationed that strongly, because there are so few at the hospital. It's scary how much he is likely spreading coronavirus because he doesn't have adequate protection. Please, save the masks for the medical professionals, so they can work on treating the patients, rather than spreading the virus.
Marty Mitchell wrote: The managers promptly pulled her into their office and forced her to remove the mask. They said it was "Scaring patients" (customers).
She had a good hard panic cry after work that night.
Marty Mitchell wrote:
Many states are now in lockdown. If lockdown lasts more than say 3 months and food is all gone within a month. I expect mass starvation to ensue.
F Agricola wrote:The USA produces more than enough food to feed itself - it won't starve by any stretch of the imagination.
Bryant RedHawk wrote:Since this thread asks about whether or not we are in a pandemic, and I am part of one of the many teams working on understanding this covid-19 virus, I can confirm that this is a very real Pandemic.
Tj Jefferson wrote:Greetings all. I have struggled with how to be a resource on here for some time. I'm going to take a leap. The fact that people are engaged, reading responsible sources and seem to be making cogent arguments on here makes me feel its a good place to comment.
I know there are lots of people who have questions and I may have some input. Most people on here don't know what I do professionally, and frankly I prefer it- people either treat me as more important than I am or like a sellout, but I'm just a regular guy with a job, until pretty recently. Everything that follows is my opinion, and I strongly encourage people to make your own decisions. I'm just trying to give some data as I see it, especially from a Permie perspective. I really appreciate prior people who have given their professional expertise to me on here, and maybe I can be of imperfect service. I will try to be responsive but I am very busy and getting more so. I do think this is a mission I can undertake to hopefully help people with their anxiety over the situation.
I'm an anesthesiologist, which is a very exposed career field at this point. The exposure and illness rates are high in ER and downstream in the treatment pathway, especially in nurses. They need your assistance and prayers, and maybe some crowdsourcing is in order, there is no happy ending without community engagement. That means many of us have been following this for months (as you can see from my prior writings in January) and trying to learn from China, Italy and the PNW here as best as possible. We are all keen on seeing as few of you as possible because we don't have a ton of solutions. I am not trying to give "inside baseball" info, more trying to translate what I think we know to you guys as you desire. Again, the data is really really patchy, and there are smart people who will disagree with me on pretty much everything. I come from more of a precautionary principle perspective, but I would say I also think there is a confidence interval, and we have to be risk averse but not paralyzed. I will try to give citations for things that I can, but I would rather synthesize my thoughts and see what questions people have. I will be available today, I have some conference calls later but will try to at least write tidbits in response. Lord willing I will try to add what I can when I am off shift. I'm going to concentrate on things that are not readily available and noncontroversial, more like what extended family are asking me. hopefully practical stuff... I'm especially involved with ad hoc protection of EMS and can give some ideas. Not data driven, but based on my best guess. I don't trust anything from the WHO and the CDC is more about decreasing panic (which is fine) than giving out mitigation strategies.
Here are a couple links to give some ideas:
Reuse of N95- from the inventor
Waste Stream N95 equivilent masks